Gene description for Mlkl
Gene name	mixed lineage kinase domain-like
Gene symbol	Mlkl
Other names/aliases	9130019I15Rik
Species	Mus musculus
Experiment description of studies that identified Mlkl in Embryonic fibroblasts
1 Experiment ID 1867 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36063142    Organism Mus musculus Experiment description Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Authors Gupta K, Brown KA, Hsieh ML, Hoover BM, Wang J, Khoury MK, Pilli VSS, Beyer RSH, Voruganti NR, Chaudhary S, Roberts DS, Murphy RM, Hong S, Ge Y, Liu B. Journal name J Extracell Vesicles Publication year 2022 Sample Embryonic fibroblasts Sample name E12.5 from Ripk3+/+ mice Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry EV-TRACK -
2 Experiment ID 1885 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36063142    Organism Mus musculus Experiment description Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Authors Gupta K, Brown KA, Hsieh ML, Hoover BM, Wang J, Khoury MK, Pilli VSS, Beyer RSH, Voruganti NR, Chaudhary S, Roberts DS, Murphy RM, Hong S, Ge Y, Liu B. Journal name J Extracell Vesicles Publication year 2022 Sample Embryonic fibroblasts Sample name MEFs from C57BL/6 mice Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry EV-TRACK -
3 Experiment ID 1887 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36063142    Organism Mus musculus Experiment description Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Authors Gupta K, Brown KA, Hsieh ML, Hoover BM, Wang J, Khoury MK, Pilli VSS, Beyer RSH, Voruganti NR, Chaudhary S, Roberts DS, Murphy RM, Hong S, Ge Y, Liu B. Journal name J Extracell Vesicles Publication year 2022 Sample Embryonic fibroblasts Sample name MEFs from C57BL/6 mice Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry EV-TRACK -
4 Experiment ID 1889 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36063142    Organism Mus musculus Experiment description Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Authors Gupta K, Brown KA, Hsieh ML, Hoover BM, Wang J, Khoury MK, Pilli VSS, Beyer RSH, Voruganti NR, Chaudhary S, Roberts DS, Murphy RM, Hong S, Ge Y, Liu B. Journal name J Extracell Vesicles Publication year 2022 Sample Embryonic fibroblasts Sample name MEFs from C57BL/6 mice Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
5 Experiment ID 1895 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 36063142    Organism Mus musculus Experiment description Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Authors Gupta K, Brown KA, Hsieh ML, Hoover BM, Wang J, Khoury MK, Pilli VSS, Beyer RSH, Voruganti NR, Chaudhary S, Roberts DS, Murphy RM, Hong S, Ge Y, Liu B. Journal name J Extracell Vesicles Publication year 2022 Sample Embryonic fibroblasts Sample name MEFs from C57BL/6 mice Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -